Publication 2086

Varela F. J., Lachaux J.-P., Rodriguez E. & Martinerie J. (2001) The brainweb: Phase synchronization and large-scale integration. Nature Reviews Neuroscience 2: 229–239. Fulltext at https://cepa.info/2086
The emergence of a unified cognitive moment relies on the coordination of scattered mosaics of functionally specialized brain regions. Here we review the mechanisms of large-scale integration that counterbalance the distributed anatomical and functional organization of brain activity to enable the emergence of coherent behaviour and cognition. Although the mechanisms involved in large-scale integration are still largely unknown, we argue that the most plausible candidate is the formation of dynamic links mediated by synchrony over multiple frequency bands.

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