Publication 4454

Petitmengin C., Navarro V. & Baulac M. (2006) Seizure anticipation: Are neuro-phenomenological approaches able to detect preictal symptoms? Epilepsy and Behavior 9: 298–306. Fulltext at
Analysis of electroencephalographic signals and several brain imaging studies suggest that a preictal state precedes the onset of seizures. In this study, we used phenomenological strategies to detect modifications in patients’ experience before their seizures. We observed that patients with partial epilepsy feeling an aura (n = 9) frequently experienced prodromes (n = 6). Prodromes were subtle preictal symptoms, varying among patients and having common negative features. They were generally continuous before seizures and could last hours, whereas auras were sudden and intermittent. All patients were able to recognize facilitating factors. We also found that patients spontaneously develop cognitive countermeasures to avoid facilitating factors (n = 6), to prevent a seizure (n = 1) or to interrupt a seizure (n = 5). Prodromes are not specific enough for clinical use, but could refine the behavioral strategies used in the treatment of epilepsy and the pathophysiology of the preictal state.


The publication has not yet bookmarked in any reading list

You cannot bookmark this publication into a reading list because you are not member of any
Log in to create one.

There are currently no annotations

To add an annotation you need to log in first

Download statistics

Log in to view the download statistics for this publication
Export bibliographic details as: CF Format · APA · BibTex · EndNote · Harvard · MLA · Nature · RIS · Science