The paper proposes a renewal of the problem-space in which the relation between psychoanalysis and the cognitive neurosciences is played out, this is in response to the persistent embarrassment or stand-off that characterizes current attempts at dialogue. The authors suggest going beyond classical conceptual oppositions, (mind-body, subject-object etc.), and beyond the seduction of the idea of some ‘natural’ conceptual translation between the two practices. A process of reciprocal ‘transference’ becomes central to creating the space in which the “mixed,” (both biological and subjective), quality of our objects may be recognized and the pitfalls of reductionism be avoided. For psychoanalysis the hysteric was originally such a mixed or “quasiobject’ in which psyche and soma were in a relation of reciprocal representation. On the other hand, the cognitive neurosciences’ ‘embodied-enactive’ and neurophenomenological perspectives provide a philosophical framework for the place of subjectivity and interpretation in scientific work. This important epistemological shift in scientific thinking offers evocative conceptual tools (emergent processes, circular causality), which should transform the difficult dialogue between the neurosciences and psychoanalysis.

Key words: Cognitive Neurosciences, Quasi-object, Consciousness, Phenomenology, Lacan

Little has been done yet to study the synchronization properties of the sources estimated from the MEG/EEG inverse problem, despite the growing interest in the role of phase relations in brain functions. In order to achieve this aim, we propose a novel approach to the MEG/EEG inverse problem based on some regularization using spectral priors: The MEG/EEG raw data are filtered in a frequency band of interest and blurred with some specific “regularization noise” prior to the inversion process. This formalism uses non quadratic regularization and a deterministic optimization algorithm. We proceed to Monte Carlo simulations using the chaotic Rössler oscillators to model the neural generators. Our results demonstate that it is possible to reveal some phase-locking between brain sources with great accuracy following the computation of the inverse problem based on scalp MEG/EEG measurements.

From the introduction: We will argue that OCD patients testify to the general condition that exercising an increased conscious control over actions can in fact diminish the sense of agency rather than increase the experience of freedom. Referring to Heidegger and Merleau-Ponty we argue that conscious control and deliberation may be useful when the natural flow of action is disturbed: for instance when a necessary tool is broken or missing or when one learns a new skill. However, deliberation itself may also disturb the flow of unreflective action. Too much deliberation on and analysis of one’s unreflective, habitual actions may cause insecurity and even a breakdown of what was once ‘second nature’. We introduce three different ways in which too much deliberation can have negative effects on patients with OCD, rendering them even more unfree.

Key words: Obsessive-Compulsive Disorder, free will, Heidegger, Merleau-Ponty, conscious control, phenomenology

Phantom perceptions arise almost universally in people who sustain sensory deafferentation, and in multiple sensory domains. The question arises ‘why’ the brain creates these false percepts in the absence of an external stimulus? The model proposed answers this question by stating that our brain works in a Bayesian way, and that its main function is to reduce environmental uncertainty, based on the freeenergy principle, which has been proposed as a universal principle governing adaptive brain function and structure. The Bayesian brain can be conceptualized as a probability machine that constantly makes predictions about the world and then updates them based on what it receives from the senses. The freeenergy principle states that the brain must minimize its Shannonian free-energy, i.e. must reduce by the process of perception its uncertainty (its prediction errors) about its environment. As completely predictable stimuli do not reduce uncertainty, they are not worthwhile of conscious processing. Unpredictable things on the other hand are not to be ignored, because it is crucial to experience them to update our understanding of the environment. Deafferentation leads to topographically restricted prediction errors based on temporal or spatial incongruity. This leads to an increase in topographically restricted uncertainty, which should be adaptively addressed by plastic repair mechanisms in the respective sensory cortex or via (para)hippocampal involvement. Neuroanatomically, filling in as a compensation for missing information also activates the anterior cingulate and insula, areas also involved in salience, stress and essential for stimulus detection. Associated with sensory cortex hyperactivity and decreased inhibition or map plasticity this will result in the perception of the false information created by the deafferented sensory areas, as a way to reduce increased topographically restricted uncertainty associated with the deafferentation. In conclusion, the Bayesian updating of knowledge via active sensory exploration of the environment, driven by the Shannonian free-energy principle, provides an explanation for the generation of phantom percepts, as a way to reduce uncertainty, to make sense of the world.

Open peer commentary on the target article “Who Conceives of Society?” by Ernst von Glasersfeld. Excerpt: While von Glasersfeld’s “epistemological model involves consciousness, memory, and some basic values” (§47), our argument from an enactive perspective is that these axiomatic elements are not atomic and already imply the participation of those social processes they intend to ground and that this fundamental intervention happens before these processes are constituted as knowable by the individual mind they shape.

Enactive approaches foreground the role of interpersonal interaction in explanations of social understanding. This motivates, in combination with a recent interest in neuroscientific studies involving actual interactions, the question of how interactive processes relate to neural mechanisms involved in social understanding. We introduce the Interactive Brain Hypothesis (IBH) in order to map the spectrum of possible relations between social interaction and neural processes. The hypothesis states that interactive experience and skills play enabling roles in both the development and current function of social brain mechanisms, even in the absence of immediate interaction. We examine the plausibility of this hypothesis against developmental and neurobiological evidence and contrast it with the widespread assumption that mindreading is crucial to all social cognition. We describe the elements of social interaction that bear most directly on this hypothesis and discuss the empirical possibilities open to social neuroscience. The link between coordination dynamics and social understanding can be grasped by studying transitions between coordination states. These transitions form part of the self-organization of interaction processes that characterize the dynamics of social engagement. The patterns of this self-organization help explain how individuals understand each other. Various possibilities for role-taking emerge during interaction, determining a spectrum of participation. This view contrasts sharply with the observational stance that has guided research in social neuroscience until recently. We also introduce the concept of readiness to interact to describe the practices and dispositions that are summoned in situations of social significance. Relevance: The paper derives in explicit form some of the empirical neuroscientific implications of the enactive approach to intersubjectivity.

Phenomenology and physiology become commensurable through a self-organizational physiology and an “enactive” view of consciousness. Selforganizing processes appropriate and replace their own needed substrata, rather than merely being caused by interacting components. Biochemists apply this notion to the living/ nonliving distinction. An enactive approach sees consciousness as actively executed by an agent rather than passively reacting to stimuli. Perception does not result from mere stimulation of brain areas by sensory impulses; unless motivated organismic purposes first anticipate and “look for” emotionally relevant stimuli, brain-sensory processing is not accompanied by perceptual consciousness. To see a soccer ball requires looking for it in the right place. The self-organizing, emotionally motivated agent instigates this looking for activity.

This paper reports on the Kuhnian revolution now occurring in neuropsychology that is finally supportive of and friendly to phenomenology – the “enactive” approach to the mind-body relation, grounded in the notion of self-organization, which is consistent with Husserl and Merleau-Ponty on virtually every point. According to the enactive approach, human minds understand the world by virtue of the ways our bodies can act relative to it, or the ways we can imagine acting. This requires that action be distinguished from passivity, that the mental be approached from a first person perspective, and that the cognitive capacities of the brain be grounded in the emotional and motivational processes that guide action and anticipate action affordances. It avoids the old intractable problems inherent in the computationalist approaches of twentieth century atomism and radical empiricism, and again allows phenomenology to bridge to neuropsychology in the way Merleau-Ponty was already doing over half a century ago.

Key words: occipital lobe, causal power, john benjamin, phenomenal consciousness, efferent activity.

It has long been theorised that there are two temporally distinct forms of self-reference: extended self-reference linking experiences across time, and momentary self-reference centred on the present. To characterise these two aspects of awareness, we used functional magnetic resonance imaging (fMRI) to examine monitoring of enduring traits (’narrative’ focus, NF) or momentary experience (’experiential’ focus, EF) in both novice participants and those having attended an 8 week course in mindfulness meditation, a program that trains individuals to develop focused attention on the present. In novices, EF yielded focal reductions in self-referential cortical midline regions (medial prefrontal cortex, mPFC) associated with NF. In trained participants, EF resulted in more marked and pervasive reductions in the mPFC, and increased engagement of a right lateralised network, comprising the lateral PFC and viscerosomatic areas such as the insula, secondary somatosensory cortex and inferior parietal lobule. Functional connectivity analyses further demonstrated a strong coupling between the right insula and the mPFC in novices that was uncoupled in the mindfulness group. These results suggest a fundamental neural dissociation between two distinct forms of self-awareness that are habitually integrated but can be dissociated through attentional training: the self across time and in the present moment.

Key words: self-reference, attention, meditation, fmri, insula, prefrontal cortex, somatosensory, plasticity

Current research on spontaneous, self-generated brain rhythms and dynamic neural network coordination cast new light on Immanuel Kant’s idea of the ‘spontaneity’ of cognition, that is, the mind’s capacity to organize and synthesize sensory stimuli in novel, unprecedented ways. Nevertheless, determining the precise nature of the brain-cognition mapping remains an outstanding challenge. Neurophenomenology, which uses phenomenological information about the variability of subjective experience in order to illuminate the variability of brain dynamics, offers a promising method for addressing this challenge.