The application of social constructivist thought and the concept of autopoiesis are discussed in relationship to the clinical practice of psychotherapy. After a brief discussion of these concepts, a theoretical basis for clinical practice is presented, focusing on the idea that human systems are essentially meaning generating systems. The concept of Problem Determined Systems is elaborated. The development of problem definitions, the management of the therapeutic conversation, and revised conceptualisations of the psychotherapeutic endeavour are discussed.
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