At a conference last month called Investigating the Mind, held here at the Massachusetts Institute of Technology, neuroscientists and Buddhist scholars discussed attention, mental imagery, emotion, and collaborations to test insights gleaned from meditation.

Open peer commentary on the article “The Past, Present and Future of Time-Consciousness: From Husserl to Varela and Beyond” by Shaun Gallagher. Upshot: A triple schematic connection between affect, action and time-consciousness can be represented as follows: “affect → action (anticipation) → time-consciousness (protention.” Two questions are raised: what is the exact directional causality between these three phenomena? And does empirical evidence from the study of certain conditions where the time-experience, affect and action were shown to be transformed support the proposed connections? While psychiatric disorders show a similar schematic causation between these phenomena, this is not the case for meditation. One possible explanation of the inconsistency is the question of the interplay in affect between arousal and valence.

Buddhism originated and developed in an Indian cultural context that featured many first-person practices for producing and exploring states of consciousness through the systematic training of attention. In contrast, the dominant methods of investigating the mind in Western cognitive science have emphasized third-person observation of the brain and behavior. In this chapter, we explore how these two different projects might prove mutually beneficial. We lay the groundwork for a cross-cultural cognitive science by using one traditional Buddhist model of the mind – that of the five aggregates – as a lens for examining contemporary cognitive science conceptions of consciousness.

Key words: Mindfulness, Attention, Consciousness, Buddhism, Meditation

Meditation experiences are viewed from a constructivist perspective. Concentrative and mindfulness approaches are compared. It is concluded that, although these meditative techniques differ (and often are used in conjunction), they both yield insight into how the mind processes experience at both the preverbal and verbal levels.

It has long been theorised that there are two temporally distinct forms of self-reference: extended self-reference linking experiences across time, and momentary self-reference centred on the present. To characterise these two aspects of awareness, we used functional magnetic resonance imaging (fMRI) to examine monitoring of enduring traits (’narrative’ focus, NF) or momentary experience (’experiential’ focus, EF) in both novice participants and those having attended an 8 week course in mindfulness meditation, a program that trains individuals to develop focused attention on the present. In novices, EF yielded focal reductions in self-referential cortical midline regions (medial prefrontal cortex, mPFC) associated with NF. In trained participants, EF resulted in more marked and pervasive reductions in the mPFC, and increased engagement of a right lateralised network, comprising the lateral PFC and viscerosomatic areas such as the insula, secondary somatosensory cortex and inferior parietal lobule. Functional connectivity analyses further demonstrated a strong coupling between the right insula and the mPFC in novices that was uncoupled in the mindfulness group. These results suggest a fundamental neural dissociation between two distinct forms of self-awareness that are habitually integrated but can be dissociated through attentional training: the self across time and in the present moment.

Key words: self-reference, attention, meditation, fmri, insula, prefrontal cortex, somatosensory, plasticity

Insights into the nondual relationship of organism and environment and their processual nature have resulted in numerous efforts at understanding human behavior and motivation from a holistic and contextual perspective. Meadian social theory, cultural historical activity theory (CHAT), ecological psychology, and some interpretations of complexity theory persist in relating human activity to the wider and more scientifically valid view that a process metaphysics suggests. I would like to articulate a concept from ecological psychology – that of affordance – and relate it to aspects of phenomenology and neuroscience such that interpretations of the self, cognition, and the brain are understood as similar to interpretations of molar behaviors exhibited in social processes. Experience with meditation as a method of joining normal reflective consciousness with “awareness” is described and suggested as a useful tool in coming to better understand the nondual nature of the body. Relevance: The article directly addresses problems and strategies for conceptualizing and working with nondual phenomena and the paradoxes therein.

Stress-related illness presents an ever-increasing burden to society, and thus has become the target of numerous complementary and integrative medicine interventions. One such clinical intervention, mindfulness meditation, has gained eminence for its demonstrated efficacy in reducing stress and improving health outcomes. Despite its prominence, little is known about the mechanics through which it exerts its treatment effects. This article details the therapeutic mechanisms of mindfulness with a novel causal model of stress, metacognition, and coping. Mindfulness is hypothesized to bolster coping processes by augmenting positive reappraisal, mitigating catastrophizing, and engendering self-transcendence. Reviews of stress and mindfulness are then framed by the perspective of second-order cybernetics, a transdisciplinary conceptual framework which builds on extant theory by highlighting the recursion between the individual and their environment.

Key words: mindfulness, stress, coping, second-order cybernetics, metacognition

Recent advances in brain imaging have improved the measure of neural processes related to perceptual, cognitive and affective functions, yet the relation between brain activity and subjective experience remains poorly characterized. In part, it is a challenge to obtain reliable accounts of participant’s experience in such studies. Here we addressed this limitation by utilizing experienced meditators who are expert in introspection. We tested a novel method to link objective and subjective data, using real-time fMRI (rt-fMRI) to provide participants with feedback of their own brain activity during an ongoing task. We provided real-time feedback during a focused attention task from the posterior cingulate cortex, a hub of the default mode network shown to be activated during mind-wandering and deactivated during meditation. In a first experiment, both meditators and non-meditators reported significant correspondence between the feedback graph and their subjective experience of focused attention and mind-wandering. When instructed to volitionally decrease the feedback graph, meditators, but not non-meditators, showed significant deactivation of the posterior cingulate cortex. We were able to replicate these results in a separate group of meditators using a novel step-wise rt-fMRI discovery protocol in which participants were not provided with prior knowledge of the expected relationship between their experience and the feedback graph (i.e., focused attention versus mind-wandering). These findings support the feasibility of using rt-fMRI to link objective measures of brain activity with reports of ongoing subjective experience in cognitive neuroscience research, and demonstrate the generalization of expertise in introspective awareness to novel contexts.

Key words: Real-time neurofeedback, Real-time fMRI, Focused attention, Posterior cingulate cortex, Default mode network, Meditation

Neuroscientific scanning of meditators is taken as providing data on mystical experiences. However, problems concerning how the brain and consciousness are related cast doubts on whether any understanding of the content of meditative experiences is gained through the study of the brain. Whether neuroscience can study the subjective aspects of meditative experiences in general is also discussed. So too, whether current neuroscience can establish that there are “pure consciousness events” in mysticism is open to question. The discussion points to limitations on neuroscience’s capability to add to our understanding of the phenomenological content of mystical experiences.

Key words: constructivism, meditation, mindfulness, multiple realization, mystical experiences, neuroscience, pure consciousness event, science of consciousness

The various phenomena associated with concentrative and mindfulness meditation are conceptualized in terms of Kelly’s personal construct theory. Reports of “unstressing,” “no-thought,” “deautomatization,” and so forth are examined and described from a constructivist viewpoint. It is argued here that personal construct theory is a powerful descriptive model for making sense of meditative experiences.