The subject of the article is what the paradigmatic framework for a universal information science or informatics should be and what kind of science we can expect it to be. The mechanistic and rationalistic information processing paradigm of cognitive science is the dominating research program in this research area which is heavily dominated by computer science and informatics. It is pointed out that this logical and mechanistic approach is unable to give an understanding of human signification and its basis in the connotations of biological and social relationships. The paper then discusses – on the basis of previous work – the ontological and epistemological problems of the idea of “information science” and constructs an alternative non‐mechanistic view based on the idea of autopoiesis of second order cybernetics and Peirce’s concept of chaos and evolution. These ideas are related to the cybersemiotic framework for transdisciplinary research of information and communication which the author has developed in other papers. Cybersemiotics is an integration of second order cybernetics, Peirce’s triadic semiosis and Wittgenstein’s theory of language game to a non‐Cartesian cognitive science.

Key words: cognitive science, second order cybernetics, semiotics, information science, ontological foundation, biosemiotics, cybersemiotics, epistemology, chaos, autopoiesis, semiosphere.

The paper attempts to review the impact of Thomas A. Sebeok (1920 2001) on biosemiotics, or semiotic biology, including both his work as a theoretician in the field and his activity in organising, publishing, and communicating. The major points of his work in the field of biosemiotics concern the establishing of zoosemiotics, interpretation and development of Jakob v. Uexkull’s and Heini Hediger’s ideas, typological and comparative study of semiotic phenomena in living organisms, evolution of semiosis, the coincidence of semiosphere and biosphere, research on the history of biosemiotics. •

Key words: semiotic biology, zoosemiotics, endosemiotics, biosemiotic paradigm, semiosphere, biocommunication, theoretical biology Culture, so-called, is implanted in nature, the environment, or Umwelt, is a model generated by the organism. Semiosis links them. T. A