Superficially at odds with the idea of empirical research, autopoiesis is shown on closer study to demand a fundamental reconsideration of the empirico-theoretical relationship. This idea is developed firstly in the context of a possible methodology and secondly in the application of that methodology to a particular regulatory situ ation. The aim is to arrive at a more adequately complex understanding of the regu latory process – as well as of the process of legal sociological research itself.